In people diagnosed with early-onset Alzheimer's disease, a biomarker tool that detects shrinkage of the brain's gray matter may predict how quickly someone may progress from mild cognitive impairment...
In people diagnosed with early-onset Alzheimer's disease, a biomarker tool that detects shrinkage of the brain's gray matter may predict how quickly someone may progress from mild cognitive impairment...
Mass General Brigham Neuroscience Institute researchers have found that a pattern of brain atrophy visible on MRI could help predict how quickly people with early-onset Alzheimer's disease progress fr...
A rare combination of lifelong cognitive tracking, postmortem brain analysis, and targeted mouse experiments reveals unexpected changes in the cells that maintain the brain’s white matter. A recent s...
By tracking every identified former NFL player who died over 14 years and examining hundreds of donated brains, researchers sought to overcome a long-standing challenge in estimating the true burden o...
The adult human brain has limited capacity to repair or regenerate neurons lost to Alzheimer's disease, the most common type of dementia. Existing treatments can slow disease progression but do not re...
In a new study from Mass General Brigham, Boston University (BU), and the Concussion & CTE Foundation, researchers found evidence that at least 1-in-4 former NFL players who died between 2016 and 2021...
Alzheimer's disease (AD) accounts for 60–80% of global dementia cases, with its core pathological feature being the misfolding and aggregation of β-amyloid (Aβ) proteins in the brain. These misfolded ...
A new review revisits the J-shaped curve, wine polyphenols, cancer risk, and the modeling choices behind increasingly restrictive alcohol guidelines. Review: Interpreting the Evidence on Wine Consump...
A new framework traces the complex biological pathways linking food to brain health and asks why the same dietary pattern may not work equally for everyone. Diet as a modifiable risk factor for Alzhe...
On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem like unrelated diseases. ALS destroys moto...