Damaged myelin alters sleep brain rhythms in neurological diseases
Scientists have discovered how damage to the myelin sheath – the insulating layer around nerve fibres – affects brain activity during sleep.
In research presented on Friday at the Federation of European Neuroscience Societies (FENS) Forum 2026, Dr Mohit Dubey described how electroencephalogram (EEG) recordings in mice with damaged myelin showed electrical spikes, similar to those seen in patients with epilepsy or Alzheimer's disease (AD). These spikes occurred only when the mice were asleep. The findings may have implications for patients with multiple sclerosis (MS), AD and other neurodegenerative diseases.
Sleep disturbances are extremely common in neurological diseases such as multiple sclerosis and Alzheimer's disease, but the biological reasons for these problems remain poorly understood."
Dr. Mohit Dubey, a ZonMw Memorable Dementia Fellow at the Netherlands Institute for Neuroscience, Amsterdam, The Netherlands
Read the Full Research
For the full scientific details, study methodology, and complete article, please visit the original publisher.
Read Full Article on Publisher Website →